Augmenting Immunotherapy

Pioneering the development of integrin-targeted agonists to improve cancer immunotherapies for solid tumors and hematologic malignancies

Our Lead Molecules

Alintegimod

Overcoming aPD-1 resistance in solid tumors

Currently undergoing a Phase Ib/IIa clinical trial, alintegimod is designed to be used in combination with immune checkpoint inhibitors to safely overcome resistance to aPD-1 drugs. Learn more…

7HP935

For safer and better cell and gene therapies

Currently undergoing IND-enabling studies, 7HP935 may improve the effectiveness of CD34+ cell-based therapies for the treatment of acute leukemias and genetic disorders of the bone marrow. Learn more…

Over $34 million in grants awarded by NIH institutions and CPRIT

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2450 Holcombe Blvd., Suite J

Houston, TX 77021